Once the specific type of Cushing’s has been determined, then therapy can be instituted.ĭepending upon the type of Cushing’s disease present, treatment may vary from slow tapering of steroid therapy for Iatrogenic Cushing’s to using specific drugs to shrink down the overactive adrenal glands or surgically removing a tumor.When a client brings their pet into my office and states that they are drinking more and urinating in the house a few common diseases come to mind. These are a combination of blood tests and possibly ultrasound, MRI, or CT scanning.
This test will tell us if your dog has Cushing’s disease, but then other tests are needed to determine the type of Cushing’s disease. The most common test is an ACTH stimulation blood test. Some patients will show decreased energy, although this is often slow to develop and a subtle change. Sometimes a patient with Cushing’s disease is presented due to lack of hair regrowth after surgery. These pets often have a poor hair coat and thin skin. A “potbellied” appearance is often seen due to an enlarged liver and weakened muscles. The most common clinical signs are increased appetite, water consumption, and urination.
In these cases, surgery and/or radiation therapy may help, but the prognosis is guarded. Occasionally the tumors can become quite large, resulting in abnormal neurological behavior. When the tumors are small, most of these patients can be treated medically. A majority of these tumors are small and primarily cause disease by producing a hormone that subsequently stimulates the adrenal gland to produce too much steroid. Fortunately, this is the least common form of Cushing’s disease. If malignant, medical and/or surgical treatment may help for a while, but the prognosis is guarded.
Benign tumors can often be treated successfully with surgery. Although these medications are given for a medical reason, the excess can lead to Cushing’s syndrome. Injections or oral administration of steroids (Iatrogenic Cushing’s disease).Corticosteroids are necessary for normal body function, but the excessive production can lead to a variety of secondary diseases. The production of these hormones is regulated by an area in the brain called the pituitary gland and produced by the adrenal glands located near the kidneys. Cushing’s disease or syndrome (Hyperadrenocorticism) is caused when an excessive amount of certain hormones, called corticosteroids, are present in the body.
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